HELICOBACTER PYLORI (PDF: 2,9 MB)
Belgrade, 1999.

Tomica Milosavljević
Ivan Jovanović

The discovery of Helicobacter Pylori infection represents an important moment of a new method of understanding chronic gastritis pathogenesis, ulcus disease but other diseases as well, such as MALT lymphoma and gaster carcinoma.

Infection has a pandemic prevalence because it is considered that half of the world population has Helicobacter Pylori on their mucous membrane. Infection prevalence is directly connected to poor socioeconomic standard of living, increased number of family members, decrease of space for living and bad hygiene. In economically more developed countries, the infection occurs more often in older population, especially after 50th year.

Clinical outcome of the infection depends on the proportion of microorganisms of the host and factors of the environment. The largest number of persons, almost 90% of them show no discomforts and they should not be regarded sick. Depending on the gene predisposing, the infection can appear in various ways.